organoids Archives - TPR: The Public's Radio

Researchers created an assembloid by integrating four organoids that represent the four components of the human sensory pathway, along which pain stimuli signals are conveyed to the brain. Stimulation of the sensory organoid (top) by pain-inducing substances, such as capsaicin, triggers neuronal activity in that organoid which is then transmitted to the adjacent spinal-cord organoid, the thalamic organoid and, finally, to the cortical organoid (bottom)

NPR

Pain pathway in a dish could aid search for new analgesic drugs

by Jon Hamilton April 10, 2025April 10, 2025

Scientists have recreated a pathway that senses pain, using clusters of human nerve cells grown in a dish.

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